MakatiMed Explains How Hormones Can Influence Breast Cancer and Why Early Detection Matters
Hormones play a powerful role in a woman’s body, from regulating mood and reproductive health to supporting bone and brain function. But did you know that hormonal imbalance or prolonged exposure to certain hormones can also increase the risk of developing breast cancer?
In recognition of Breast Cancer Awareness Month, Makati Medical Center (MakatiMed) sheds light on the link between hormones and breast cancer, emphasizing the importance of early screening and advanced imaging for timely diagnosis and effective treatment.
Understanding the Hormonal Link to Breast Cancer
Two key hormones, estrogen and progesterone, are essential for maintaining a woman’s reproductive health. Estrogen regulates the menstrual cycle, while progesterone prepares the uterus for pregnancy and supports milk production.
However, excessive or prolonged exposure to these hormones can increase the risk of hormone-sensitive breast cancer, as they fuel the growth of hormone-dependent cancer cells.
“Hormone-sensitive breast cancer cells contain hormone receptors—estrogen receptors (ERs) and progesterone receptors (PRs). When hormones bind to these receptors, they activate certain genes that trigger cell growth,” explains Dr. Melodie Grace M. Remorca from MakatiMed’s Breast Imaging Center.
According to the American Cancer Society, about two out of three breast cancers are hormone receptor-positive, meaning they respond to estrogen or progesterone.
Hormone Therapy: A Key Treatment Option
Hormone-sensitive breast cancers can be treated with hormone therapy, which works by either reducing the body’s production of estrogen and progesterone or blocking hormones from binding to cancer cells.
Dr. Remorca shares that depending on the treatment type, hormone therapy can:
- Slow down or stop the growth of hormone-driven cancer cells
- Lower the risk of the cancer returning
- Be used before surgery to shrink tumors or after surgery to prevent recurrence
Patients typically take hormone therapy for at least five years, often alongside surgery, chemotherapy, or radiation therapy.
“Hormone therapy has proven effective in reducing the risk of recurrence and improving survival rates,” Dr. Remorca adds. “Still, early detection remains key to the best outcomes.”
Why Early Screening Saves Lives
Common symptoms of breast cancer include a lump in the breast, nipple discharge or inversion, and changes in breast shape or size. Anyone experiencing these signs should consult a specialist immediately for screening.
Since 1993, MakatiMed’s Breast Imaging Center has been a pioneer in breast imaging in the Philippines, offering state-of-the-art services such as:
- Digital Breast Tomosynthesis (3D Mammography)
- Breast Ultrasound (Sonomammogram)
- Ultrasound- and Stereotactic-Guided Biopsies
- Cyst and Fine Needle Aspiration
- Wire Needle Localization and Galactography
The center’s all-women team of expert radiologists, technologists, and nurses provides comprehensive care in a supportive environment, helping patients through every step of diagnosis and treatment.
While genetics and lifestyle play a role in breast cancer risk, hormonal factors are also significant—especially for women with long-term exposure to estrogen and progesterone. The good news? With advanced imaging, personalized treatments, and increased awareness, early detection offers hope and better survival rates.
As MakatiMed continues to lead in women’s health, it reminds Filipinas that knowledge, prevention, and regular screening are their best defenses against breast cancer.
For consultations, contact MakatiMed On-Call at +632 8888 8999 or visit www.makatimed.net.ph.